The Lamb is Worthy to open the scroll
In the right hand of Him – this is more properly translated “on” or “at the right hand.”
seven seals – which shall be broken one by one. The number seven is throughout the Book of Revelation, and represents completeness: seven horns, seven eyes, seven churches, etc. God’s relationship with man on the earth is completed in seven thousand years, and God made seven days to complete a week. There are also seven communications of God and Christ that explain His plan of salvation; the first of these was “Let Us make man in Our image.”
The sixth seal, sixth trumpet and sixth bowl of wrath, all describe the battle of Armageddon that ends man’s existence. The seventh seal, trumpet, and bowl of wrath describe our resurrection to eternal rest, just as God also rested on the Sabbath. The relationship between seven thousand years of man, and the seventh Day, as representing the last thousand years, the Lord’s Day, is also described in the Epistle of Barnabas, written by the Gentiles in about 100 AD.
seven horns and seven eyes which are the seven Spirits out God sent out into all the earth – the seven eyes are the seven spirits of God described in Zechariah 4:10. A horn generally symbolizes power; see 1 Samuel 2:1, Rev 13:1, etc. Seven means perfection, or completeness. The meaning, here, is the same as Rev 1:16;20: the Spirit of Christ, as the Ruler of the Angels, and the Son of Man, holds seven Angels in His right hand. Daniel 8:11-12; and Rev 12:7-10 prophesy that the Spirit of Christ became the “Captain of the captains” when He became our Lord [Prince and Captain are the same Hebrew word]. Therefore, the seven horns also represent complete authority over the Angels.
He took the book out of the right hand – this scene really defeats any modalistic view of God and Christ. Here, we are after the Judgment Day, (Rev 5:13) and there are definitely two beings portrayed here. The Bible does not support the idea that Christ and God are the same person, or being.
Here God gives Christ the Revelation, as described in Revelation 1:1.
each holding a harp – meaning they have received the spirit of truth, which will abide with us forever, and causes the tongue to emit sound when one prays. Paul compared speaking in tongues, to the sound of a harp in 1 Corinthians 14:7. They pray in the holy spirit on behalf of all the saints.
The prayers of the saints – which are still remembered after the Judgment Day.
myriads – 10,000’s; this is from Daniel 7:10, which says “myriads and myriads standing before him” and “thousands and thousands attending to him.” The Catholic liturgy corrupted this to call the thousands of angels: “archangels.”
every created thing in heaven, and on the earth, and under the earth and on the sea – we can see the meaning of this as: all creatures, spiritual beings and men; the dead in hades, and the saved (on the sea).